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Hair is a defining character of mammals and an extension of human aesthetic sense. Poliosis is the name given to a localized patch of white hair. Most frequently, poliosis presents as a white forelock, but it can. Poliosis can occur in otherwise healthy people and. However, poliosis is also. An overview of Waardenburg syndrome, a rare genetic disease causing features like albinism and dystopia canthorum. An overview of Waardenburg. White lock of hair on the forehead; Immediate family member with Waardenburg. Waardenburg syndrome is a group of conditions passed down through families. White patch of hair or early graying of the hair. It is keratin filament that grows, and regrows, from follicles that are scattered throughout our bodies. Numerous factors affect its formation, structural variation and overall health, few of them are androgens, genetics and nutrition. Since ancient times, the parallel connection between hair and our bodily aging process has intrigued the thinkers. Science has solved many mysteries of hair growth, replenishment and change with age, but many remain confusing yet. Here, we briefly highlight the natural course of hair growth with human aging and death, discovering the causes of white hair, along with some tantalizing myths and preventive measures to keep hair damage- free and young at an old age. When does hair get old? There is no benchmark age for hair to turn white. In this case there usually are other family members with similar white patches of hair. Marfan's syndrome and Waardenburg's syndrome are other genetic. What causes a certain patch of hair on my head to turn. Waardenburg syndrome is a group of genetic conditions that can cause hearing loss and changes in coloring (pigmentation) of the hair, skin, and eyes. Some people especially those with single and small white hair patch term it as normal and they do not see any point of seeking medical care. Waardenburg’s syndrome and Marfan’s syndrome can also cause poliosis. Hair color is drastically affected by bodily health status, ethnic heritage, diseased conditions, hormones and stress. On average, though, white people get white hair in their mid- 3. Asians whose hair lose its pigment in the late 3. Black people get white hair in mid- 4. Any hair turning grey way earlier is termed as . It gets pigment, melanin, through specialized cells called melanocytes. These cells pump this pigment into the hair follicles that gives hair a characteristic color. Melanin is of two predominant types: Eomelanin (dark pigment) and Pheomelanin (light pigment). These combine in various proportions and produce a huge range of hair textures. The amount and combination of various melanin types are determined mainly by our genes. Melanocytes start their secretion even before our birth and their function regresses with our age. Generally, melanocyte function decreases 1. How melanocyte function lessens with age is a mystery. Scientists believe that our hair follicles have a . Grey hair is a precursor of white hair, and contains less or no melanin at all due to inactive melanocytes. Must Read: - What Type of Differences We Can Find Between White Hair and Gray Hair? The early scientific belief. Before scientific advancement, scientists thought that hair turned grey merely due to less or no production of melanin. Each hair has a separate melanin supply in the body. With time and age, this supply lessens, producing grey hair, which culminates in complete inability to supply the pigment to the hair, thus causing white hair permanent. The new scientific belief. Scientists have recently discovered a breakthrough in the aging process of hair. It is now believed that hair lose their pigment not due to decreased production of melanin, but increased production of hydrogen peroxide. With old age, hydrogen peroxide collects in the hair follicles and cannot be degraded as the enzyme catalase loses its ability to do so. Hydrogen peroxide acts as a bleaching agent and whitens hair from inside out. Hence, the main culprit is the failure of the enzyme catalase to work in old age. What actually causes white hair in humans? Waytru started to see gray hair when he was 1. Image Credit: Way. Tru. There are multiple causes that contribute to hair aging, each of them playing their own specific roles for targeting melanin in their own manner. Here, we look at a few that contribute most drastically. Role of genes. The pattern of hair color is determined by the family tree since greying of hair is largely dependent on genetics. Genes pretty much determine the melanogenic clock that rings right when our parents’ hair turned gray, so we follow their trademark. If your hair is prematurely graying or turning white without any disease, stress or hormonal disruption, then perhaps, your DNA is to be blamed. Of course, your off- springs will continue the same genetic path for hair graying as you did. Having white hair does not always mean that you carry a disease or bodily disruption, but they are just following a set code of instructions from our genes. Less vitamin intake. Balanced diet is the key to a healthy lifestyle. Several diet- related factors influence hair health. Vitamin deficiency is one of them, specifically deficiency of Vitamin B1. If you take Vitamin B1. In another case, lack of intake of Vitamin B1. See also: - 2. 0 Foods That Are Highly Loaded With Vitamin B1. Therefore, one major clinical symptom of Vitamin B1. To obtain the optimum amount of this vitamin, we should incorporate eggs, yogurt, cheese, fish, beef, etc. An overactive or very slow thyroid function can produce add to depigmentation of hair. It is thus recommended to get the thyroid function checked if the hair starts graying prematurely. Even when thyroid function is a little subnormal, the effects can really show on the scalp. To get treated, visit the doctor and switch to healthier diet options that contain iodine, like fish, carrots and bananas. Harmful Addictions. Taking care of health and following an active life can reduce hair fall and hair graying drastically. Unhealthy habits like smoking and drinking play a major role in premature hair whitening. Unfortunately, these effects are reversible and the outcomes are very fruitful. Quitting smoking will decelerate whitening of hair by 4% in young people. Genetic factors and disease cannot be reversed at will, but unhealthy lifestyle can. The healthier you are, the better it will show on your skin and hair. Unbalanced diet. It is said that you are what you eat. Hence, eating a well- balanced diet will provide you all the nutrition your body needs. This complements the overall health of the body, and includes hair too. Intake of nutrient- rich diet will keep you fit and healthy on the outside and inside, combating whitening of hair to a greater extent. So hair will shine with their natural color even at a vulnerable age. Intake of fluids. Hair need as much fluid for optimal growth and nourishment as any other part of our body. What you drink casually or what harmful drinks we are addicted to can serve as a harbinger to hair discoloration. Be it merely tea and coffee or infamous alcohol, too much of everything retards hair growth and ages hair fast. It is preferable to limit intake of specific fluids when hair starts whitening prematurely. Also, fried food and excessive oil intake in any manner is never advisable. Sudden trauma. It is undeniable that our emotional health is as integral as physical and mental well being. Emotional shock due to a bad news, heartbreak or an accident can play havoc for hair health. Although this concept is controversial, scientists still believe that such a mental shock can temporarily retard hair growth. The underlying complex mechanism is still debatable, but the relation between trauma and growth graying can never be underestimated. The effect varies from person to person, but incidences of alopecia areata have been reported after several trauma exposures. Alopecia areata. While “overnight greying of hair” is an unbelievable happening, there exists a medical condition that people can misjudge as an overnight hair graying. Although rare, this disease causes loss of hair from some or all parts of the body instantaneously. It is medically defined as non- scarring, loss of body hair from underlying causes such as inflammation. Hair loss can also occur in a patchy manner from the scalp, lowering the person’s self- esteem and emotional well being. Hair growth may resume afterwards, but the new hair would have no pigment – they will most likely turn grey or white prematurely. Weber’s Syndrome. Certain irreversible autoimmune or genetic diseases can have severe outcomes: one of them is hair graying and hair loss. The uncommon genetic disease, called Weber’s syndrome, is a collection of symptoms that indicate senile behavior at an early as of teenagers. In other words, a person as young as 2. Weber’s syndrome will look like a 6. Obviously, hair will grow white at this early age due to rapid aging, ending in early death. Hormonal imbalance. Hormones are released from endocrine organs of our body and keep the bodily functions in a complex way. A small imbalance in secretion or function of hormones can badly disturb the overall body balance. Every day, scientific research is proving that hormonal problems add to graying hair. Medical conditions that results from these hormonal imbalances such as osteoporosis and diabetes can highly accelerate hair aging too. The root cause is the decreased melanocyte cell pigmentation which results from high or low hormone levels in the body. Vitiligo. As mentioned earlier, several irreversible medical conditions harm hair growth and pigmentation. One of those is vitiligo. It is a form of albinism that leaves patches of hair and skin unpigmented. The underlying problem is with the immune system which mistakenly attacks its own scalp rather than a foreign antigen. Another interpretation involves the failure to get rid of accumulated hydrogen peroxide in this disease, hence white hair results. Whatever be the major cause, vitiligo is a massive pigmentation disorder involving the melanocytes and leaves the body hair, patched with various shades of grey and white. Anemia. Anemia is one condition that is linked to countless bad outcomes. Anemia itself can occur due to many reasons, such as less production or high destruction of blood cells by the body, infections, prolonged bleeding, ulcers and nutrition deficiency. Must Read: - Does anemia cause white hair? Less red blood cells, and hence less hemoglobin, will lessen blood supply to each hair follicle and damage hair growth. The outcomes can be premature hair greying. Anemia, therefore, should be treated as soon as diagnosed to counter all side effects and save the hair from losing their pigment. Prolonged free radical damage. Ongoing scientific research has led to another discovery of reasons of hair graying. When the body is under continued stress, cells produce certain by- products that act locally and systemically in order to overcome the stressful situation. Anderson Cancer Center Physician-Scientist Program and by NIH. TRANSLATION: DNA PROTEIN. DNA to Protein Translation Calculator.DNA< -> RNA- > protein. Converts DNA to RNA to protein. Starting the protein synthesis machine: eukaryotic translation initiation. Thank you for choosing to send your work entitled “Regulation of protein translation during. 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